About   Help   FAQ
Braptm1.2Yfng
Targeted Allele Detail
Summary
Symbol: Braptm1.2Yfng
Name: BRCA1 associated protein; targeted mutation 1.2, Yuanyi Feng
MGI ID: MGI:7510103
Synonyms: Brapflox
Gene: Brap  Location: Chr5:121798626-121825312 bp, + strand  Genetic Position: Chr5, 61.9 cM, cytoband F
Alliance: Braptm1.2Yfng page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsThe targeting vector is designed to insert a loxP and FRT-flanked neomycin resistance (neo) cassette into intron 1 and a third loxP site into intron 3. Flp-mediated recombination removed the neo cassette. (J:197131)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Brap Mutation:  30 strains or lines available
References
Original:  J:197131 Lanctot AA, et al., Spatially dependent dynamic MAPK modulation by the nde1-lis1-brap complex patterns Mammalian CNS. Dev Cell. 2013 May 13;25(3):241-55
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory