Tg(Ccl2-EGFP)1Pame
Transgene Detail

Summary

• Symbol: Tg(Ccl2-EGFP)1Pame
• Name: transgene insertion 1, Eric G Pamer
• MGI ID: MGI:7509722
• Synonyms: Ccl2.GFP
• Transgene: Tg(Ccl2-EGFP)1Pame Location: unknown
• Alliance: Tg(Ccl2-EGFP)1Pame page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: A modified BAC construct was generated that consisted of an insertion immediately upstream of the stop codon in exon 3 of the Ccl2 gene of nucleotides encoding the HA peptide (-YPYDVPDYA-), followed by a 19 residue aphthovirus 2A cleavage site (-APVKQTLNFDLLKLAGDVESNPGP-), a furin cleavage site (-RAKR-), and aa 2239 of enhanced GFP. The EGFP coding sequence was followed by a stop codon. (J:171379)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:171379 Shi C, et al., Bone Marrow Mesenchymal Stem and Progenitor Cells Induce Monocyte Emigration in Response to Circulating Toll-like Receptor Ligands. Immunity. 2011 Apr 22;34(4):590-601
• All: 5 reference(s)