Tg(ACTB-Pdcd1)BHon
Transgene Detail

Summary

• Symbol: Tg(ACTB-Pdcd1)BHon
• Name: transgene insertion B, Tasuku Honjo
• MGI ID: MGI:7507548
• Transgene: Tg(ACTB-Pdcd1)BHon Location: unknown
• Alliance: Tg(ACTB-Pdcd1)BHon page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTB-Pdcd1)BHon expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pdcd1 (MGI:104879)

• Tg(ACTB-Pdcd1)BHon expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  chicken	ACTB (396526)

• The transgene contains the chicken promoter, mouse PD-1 cDNA, and SV40 polyA. (J:95689)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:95689 Iwai Y, et al., PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells. Int Immunol. 2005 Feb;17(2):133-44
• All: 1 reference(s)