Gt(ROSA)26Sor^{tm1(CAG-tdTomato,-GFP)Jbr}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-tdTomato,-GFP)Jbr}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jean-Francois Brunet
• MGI ID: MGI:7506800
• Synonyms: Rosa^FTLG
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-tdTomato,-GFP)Jbr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314904
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted CAG promoter-FRT-NeoR-STOP-FRT LoxP-TdTomato-STOP-LoxP Syn-YFP cassette into Gt(ROSA)26Sor locus. It is an intersectional recombinase reporter. The Flp recombinase activity is needed to allow the expression of tdTomato. In the cell where both Flp and Cre recombinase are active, syn-YFP is expressed. (J:314904)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1098 strains or lines available

References

• Original: J:314904 Dempsey B, et al., A medullary centre for lapping in mice. Nat Commun. 2021 Nov 2;12(1):6307
• All: 2 reference(s)