Il27ra^tm1.1Yznz
Targeted Allele Detail

Summary

• Symbol: Il27ra^tm1.1Yznz
• Name: interleukin 27 receptor, alpha; targeted mutation 1.1, Zhinan Yin
• MGI ID: MGI:7496113
• Synonyms: Il27ra^flox
• Gene: Il27ra Location: Chr8:84756923-84769218 bp, - strand Genetic Position: Chr8, 40.26 cM, cytoband C3
• Alliance: Il27ra^tm1.1Yznz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:337627
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 3 and exon 4 were flanked by loxP sites and an frt-flanked neomycin selection cassette. The frt-flanked neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:337627)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il27ra Mutation: 31 strains or lines available

References

• Original: J:337627 Wang Q, et al., IL-27 signalling promotes adipocyte thermogenesis and energy expenditure. Nature. 2021 Dec;600(7888):314-318
• All: 2 reference(s)