Il33^tm2.1Cln
Targeted Allele Detail

Summary

• Symbol: Il33^tm2.1Cln
• Name: interleukin 33; targeted mutation 2.1, Marco Colonna
• MGI ID: MGI:7493617
• Synonyms: Il33-/- lacZ reporter, Il33^{tm1b(EUCOMM)Cln}
• Gene: Il33 Location: Chr19:29902514-29938118 bp, + strand Genetic Position: Chr19, 24.56 cM, cytoband C2
• Alliance: Il33^tm2.1Cln page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:251027
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A null/knockout allele was created by cre recombinase expression in mice to remove the neo selection cassette and loxP-flanked critical exon(s), leaving the lacZ sequence.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il33 Mutation: 32 strains or lines available

References

• Original: J:251027 Huang B, et al., Interleukin-33-induced expression of PIBF1 by decidual B cells protects against preterm labor. Nat Med. 2017 Jan;23(1):128-135
• All: 3 reference(s)