Fcgr2b^tm1Hros
Targeted Allele Detail

Summary

• Symbol: Fcgr2b^tm1Hros
• Name: Fc receptor, IgG, low affinity IIb; targeted mutation 2, Sachiko Hirose
• MGI ID: MGI:7493415
• Gene: Fcgr2b Location: Chr1:170786186-170804116 bp, - strand Genetic Position: Chr1, 78.02 cM
• Alliance: Fcgr2b^tm1Hros page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137977
• Parent Cell Line: BL/6-III (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced exon 2 with a neomycin resistance cassette. (J:137977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fcgr2b Mutation: 49 strains or lines available

References

• Original: J:137977 Lin Q, et al., Genetic dissection of the effects of stimulatory and inhibitory IgG Fc receptors on murine lupus. J Immunol. 2006 Aug 1;177(3):1646-54
• All: 1 reference(s)