Spib^tm2.1Ksho
Targeted Allele Detail

Summary

• Symbol: Spib^tm2.1Ksho
• Name: Spi-B transcription factor (Spi-1/PU.1 related); targeted mutation 2.1, Tsuneyasu Kaisho
• MGI ID: MGI:7493209
• Gene: Spib Location: Chr7:44175417-44181495 bp, - strand Genetic Position: Chr7, 28.83 cM
• Alliance: Spib^tm2.1Ksho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104881
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site and an FRT-flanked MC1-promoter driven neomycin resistance gene cassette were inserted upstream of exon 6 and a second loxP site was inserted downstream of exon 6. The neomycin cassette was removed via flp-mediated recombination leaving exon 6 floxed. (J:104881, J:347060)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Spib Mutation: 23 strains or lines available

References

• Original: J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013
• All: 2 reference(s)