Cd160^tm1Shr
Targeted Allele Detail

Summary

• Symbol: Cd160^tm1Shr
• Name: CD160 antigen; targeted mutation 1, Arlene H Sharpe
• MGI ID: MGI:7491748
• Gene: Cd160 Location: Chr3:96706079-96736667 bp, - strand Genetic Position: Chr3, 41.99 cM
• Alliance: Cd160^tm1Shr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:329800
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin selection cassette replaced exons 2 and 3 encoding the signal sequence and Ig-V, respectively. (J:329800)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd160 Mutation: 16 strains or lines available

References

• Original: J:329800 Tan CL, et al., CD160 Stimulates CD8(+) T Cell Responses and Is Required for Optimal Protective Immunity to Listeria monocytogenes. Immunohorizons. 2018 Aug 27;2(7):238-250
• All: 2 reference(s)