Ntrk1^em1Tkato
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ntrk1^em1Tkato
• Name: neurotrophic tyrosine kinase, receptor, type 1; endonuclease-mediated mutation 1, Tadafumi Kato
• MGI ID: MGI:7490181
• Synonyms: Ntrk1 (CRISPR, 268-1), Ntrk1^{em1(E495K)Tkato}
• Gene: Ntrk1 Location: Chr3:87685551-87702469 bp, - strand Genetic Position: Chr3, 38.62 cM
• Alliance: Ntrk1^em1Tkato page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting introduced the mutation responsible for the amino acid substitution of glutamate with lysine at position 495 (E495K). (J:336592)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ntrk1 Mutation: 60 strains or lines available

References

• Original: J:336592 Nakajima K, et al., Exome sequencing in the knockin mice generated using the CRISPR/Cas system. Sci Rep. 2016 Oct 4;6:34703
• All: 1 reference(s)