Plin2^em1Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Plin2^em1Tcp
• Name: perilipin 2; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:7489806
• Gene: Plin2 Location: Chr4:86566623-86588297 bp, - strand Genetic Position: Chr4, 40.69 cM
• Alliance: Plin2^em1Tcp page

Mutation origin

• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: This knockin allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with guide RNAs with the spacer sequences AGCAGTAGTGGATCCGCAAC. The Rosella fluorescent pH-biosensor ORF was delivered by AAV transduction and was inserted between 86586916 and 86586917 of Chr4 (GRCm39). Silent mutations were introduced in Plin2 at c.15 A>C (p.Val5), c.21 T>C(p.AspD7), and c.24 G>T (p.Pro8). (J:200814)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plin2 Mutation: 40 strains or lines available

References

• Original: J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013
• All: 1 reference(s)