Noc2l^tm1.1Rosc
Targeted Allele Detail

Summary

• Symbol: Noc2l^tm1.1Rosc
• Name: NOC2 like nucleolar associated transcriptional repressor; targeted mutation 1.1, Roland Schule
• MGI ID: MGI:7489801
• Synonyms: Nir^fl
• Gene: Noc2l Location: Chr4:156320376-156332073 bp, + strand Genetic Position: Chr4, Syntenic
• Alliance: Noc2l^tm1.1Rosc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260456
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An frt-flanked PGK neomycin resistance cassette was inserted downstream of exon 4 and two loxP sites were inserted flanking exons 5 to 12. The frt-flanked PGK neomycin resistance cassette was removed via FLP-mediated recombination in the germline. (J:260456)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Noc2l Mutation: 21 strains or lines available

References

• Original: J:260456 Duteil D, et al., The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018 Mar 21;145(6):dev158543
• All: 1 reference(s)