Abcc9^em3Cbet
Endonuclease-mediated Allele Detail

Summary

• Symbol: Abcc9^em3Cbet
• Name: ATP-binding cassette, sub-family C member 9; endonuclease-mediated mutation 3, Christer Betsholtz
• MGI ID: MGI:7489798
• Synonyms: Abcc9-tdTomato
• Gene: Abcc9 Location: Chr6:142533588-142648041 bp, - strand Genetic Position: Chr6, 74.35 cM
• Alliance: Abcc9^em3Cbet page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: Using CRISPR targeting homologous recombination, the P2A-tdTomato sequence was inserted at the location between the last amino acid and the translation termination codon in exon 40 of the Abcc9 gene. (J:325735)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abcc9 Mutation: 108 strains or lines available

References

• Original: J:325735 Ando K, et al., KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling. Dev Cell. 2022 Jun 6;57(11):1383-1399.e7
• All: 1 reference(s)