Tex15^em2Doca
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tex15^em2Doca
• Name: testis expressed gene 15 meiosis and synapsis associated; endonuclease-mediated mutation 2, Donal O'Carroll
• MGI ID: MGI:7489746
• Gene: Tex15 Location: Chr8:34006766-34075610 bp, + strand Genetic Position: Chr8, 20.59 cM
• Alliance: Tex15^em2Doca page

Mutation origin

• Strain of Origin: (C57BL/6J x CBA/CaCrl)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing technology was used to generate a 70bp insertion in exon 5 that introduces in frame stop codons and is predicted to result in a truncated protein. (J:291848)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tex15 Mutation: 115 strains or lines available

References

• Original: J:291848 Schopp T, et al., TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing. Nat Commun. 2020 Jul 27;11(1):3739
• All: 1 reference(s)