Ptgdstm1(cre)Gvn
Targeted Allele Detail
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Symbol: |
Ptgdstm1(cre)Gvn |
Name: |
prostaglandin D2 synthase (brain); targeted mutation 1, Marco Giovannini |
MGI ID: |
MGI:7488139 |
Gene: |
Ptgds Location: Chr2:25356721-25360058 bp, - strand Genetic Position: Chr2, 17.28 cM
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Alliance: |
Ptgdstm1(cre)Gvn page
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Germline Transmission: |
Earliest citation of germline transmission:
J:173718
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Ptgdstm1(cre)Gvn expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Ptgds (MGI:99261) |
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Mutation details: A targeting vector was constructed with the nls-cre recombinase sequence fused to exon 1 of the Ptgds locus and a poly A signal with a floxed EGFP-hygromycin selection cassette 3' to the cre poly A signal. Homologous recombination in ES cells was performed to replace exon 1 with the targeting construct.
(J:173718)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Ptgds
(mouse)
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Original: |
J:173718 Kalamarides M, et al., Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes. Oncogene. 2011 May 19;30(20):2333-44 |
All: |
1 reference(s) |
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