Bsn^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Bsn^tm1.1Arte
• Name: bassoon; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:7484796
• Synonyms: Bsn^lx, Bsn^tm1LIN
• Gene: Bsn Location: Chr9:107973221-108067583 bp, - strand Genetic Position: Chr9, 59.07 cM, cytoband F
• Alliance: Bsn^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:281424
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 2 was flanked by loxP sites and an FRT-flanked neomycin resistance gene was inserted in intron 1 and an F3-flanked puromycin resistance gene in intron 2. The neomycin and puromycin genes were removed via flp-mediated recombination. (J:281424)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bsn Mutation: 148 strains or lines available

References

• Original: J:281424 Annamneedi A, et al., Ablation of the presynaptic organizer Bassoon in excitatory neurons retards dentate gyrus maturation and enhances learning performance. Brain Struct Funct. 2018 Sep;223(7):3423-3445
• All: 1 reference(s)