Ccser2^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ccser2^em1(IMPC)J
• Name: coiled-coil serine rich 2; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7484552
• Gene: Ccser2 Location: Chr14:36596893-36690734 bp, - strand Genetic Position: Chr14, 21.29 cM, cytoband B
• Alliance: Ccser2^em1(IMPC)J page
• IMPC: Ccser2 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTGTATTGAGAAGTGCCCCT and CAAATGCTGTTATAATAGAT, which resulted in a 465 bp deletion beginning at Chromosome 14 position 36,938,415 bp and ending after 36,938,879 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001237712 (exon 3) and 268 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 471 and early truncation 4 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ccser2 Mutation: 58 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)