Syna^em1(cre)Mdf
Endonuclease-mediated Allele Detail

Summary

• Symbol: Syna^em1(cre)Mdf
• Name: syncytin a; endonuclease-mediated mutation 1, Mark D Fleming
• MGI ID: MGI:7484063
• Gene: Syna Location: Chr5:134587000-134589025 bp, - strand Genetic Position: Chr5, 74.67 cM
• Alliance: Syna^em1(cre)Mdf page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Syna^em1(cre)Mdf expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Syna (MGI:2684898)

• Mutation details: Using CRISPR/Cas9 methodologies a porcine teschovirus-1 2A oligopeptide (P2A) self-cleaving peptide, to mediate ribosomal skipping, fused to a Cre recombinase sequence (cre) was inserted immediately before the stop codon of the syncytin a (Syna) gene. (J:101977)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Syna (mouse) Summary of all recombinase alleles driven by Syna. Alliance mouse Syna gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Syna Mutation: 29 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)