Ackr3^tm1.1Kff
Targeted Allele Detail

Summary

• Symbol: Ackr3^tm1.1Kff
• Name: atypical chemokine receptor 3; targeted mutation 1.1, Brigitte L Kieffer
• MGI ID: MGI:7468923
• Synonyms: ACKR3-Venus
• Gene: Ackr3 Location: Chr1:90131702-90143446 bp, + strand Genetic Position: Chr1, 45.28 cM
• Alliance: Ackr3^tm1.1Kff page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:335214
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector was designed to insert Venus yellow fluorescent protein cDNA into the C-terminal of the gene. A loxP-flanked neomycin resistance cassette associated with a Cre auto-excision transgene was inserted upstream of exon 2. This cassette allows the excision of the whole cassette in the chimera's male germ line. (J:335214)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ackr3 Mutation: 34 strains or lines available

References

• Original: J:335214 Ehrlich AT, et al., Ackr3-Venus knock-in mouse lights up brain vasculature. Mol Brain. 2021 Sep 28;14(1):151
• All: 1 reference(s)