Set^em1Cguo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Set^em1Cguo
• Name: SET nuclear oncogene; endonuclease-mediated mutation 1, Changying Guo
• MGI ID: MGI:7467345
• Synonyms: I2PP2A^flox, SET^fl
• Gene: Set Location: Chr2:29952074-29962589 bp, + strand Genetic Position: Chr2, 21.09 cM
• Alliance: Set^em1Cguo page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was flanked by loxP sites via CRISPR/Cas9 technology. (J:335148)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Set Mutation: 46 strains or lines available

References

• Original: J:335148 Zhang S, et al., SET/PP2A signaling regulates macrophage positioning in hypoxic tumor regions by amplifying chemotactic responses. Exp Mol Med. 2022 Oct;54(10):1741-1755
• All: 1 reference(s)