Tg(Thy1-Lgi1)#Mafu
Transgene Detail

Summary

• Symbol: Tg(Thy1-Lgi1)#Mafu
• Name: transgene insertion, Masaki Fukata
• MGI ID: MGI:7466703
• Synonyms: LGI1-FH, Thy1-Lgi1-FH
• Transgene: Tg(Thy1-Lgi1)#Mafu Location: unknown
• Alliance: Tg(Thy1-Lgi1)#Mafu page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Thy1-Lgi1)#Mafu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Lgi1 (252892)

  Lgi1	(MGI:1861691)

  mouse promoter, rat cDNA with C-terminal FLAG and 6xHis tags

• Mutation details: The mouse Thy1 promoter drives expression of the rat Lgi1 cDNA (with sequence for a C-terminal FLAG tag and 6xHis tag inserted immediately upstream of the stop codon). (J:157578)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:157578 Fukata Y, et al., Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3799-3804
• All: 2 reference(s)