Tg(Prox1-Lgi1)#Ran
Transgene Detail

Summary

• Symbol: Tg(Prox1-Lgi1)#Ran
• Name: transgene insertion, Roger A Nicoll
• MGI ID: MGI:7466678
• Synonyms: Prox1-LGI1
• Transgene: Tg(Prox1-Lgi1)#Ran Location: unknown
• Alliance: Tg(Prox1-Lgi1)#Ran page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Prox1-Lgi1)#Ran expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Lgi1 (252892)

  Lgi1	(MGI:1861691)

  mouse promoter, rat cDNA C-terminal FLAG and 6xHis tags

• Mutation details: The transgene insert comprises mouse BAC RP23-360I16 where the rat Lgi1 cDNA (with sequence for a C-terminal FLAG tag and 6xHis tag inserted immediately downstream of the stop codon) and a kanamycin resistance gene were inserted immediately downstream of the Prox1 ATG translation start site. (J:226077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:226077 Lovero KL, et al., The LGI1-ADAM22 protein complex directs synapse maturation through regulation of PSD-95 function. Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4129-37
• All: 2 reference(s)