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Eps8em1Pgg
Endonuclease-mediated Allele Detail
Summary
Symbol: Eps8em1Pgg
Name: epidermal growth factor receptor pathway substrate 8; endonuclease-mediated mutation 1, Peter G Gillespie
MGI ID: MGI:7466157
Synonyms: Eps8delta818
Gene: Eps8  Location: Chr6:137454242-137626262 bp, - strand  Genetic Position: Chr6, 66.78 cM
Alliance: Eps8em1Pgg page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR/Cas9 technology generated a large deletion spanning 10,818 bp between exons 3 and 5. (J:334959)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Eps8 Mutation:  122 strains or lines available
References
Original:  J:334959 Halford J, et al., Ca(2+) entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips. Mol Biol Cell. 2022 Apr 1;33(4):br6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory