Tcf21^{em1(cre/ERT2)Boz}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tcf21^{em1(cre/ERT2)Boz}
• Name: transcription factor 21; endonuclease-mediated mutation 1, Bo O Zhou
• MGI ID: MGI:7464547
• Synonyms: Tcf21^creER
• Gene: Tcf21 Location: Chr10:22693162-22696042 bp, - strand Genetic Position: Chr10, 10.33 cM
• Alliance: Tcf21^{em1(cre/ERT2)Boz} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tcf21^{em1(cre/ERT2)Boz} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tcf21 (MGI:1202715)

• The creER sequence was inserted into and replaced the ATG site of the Tcf21 gene. (J:334866)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tcf21 (mouse) Summary of all recombinase alleles driven by Tcf21. Comparative matrix view of recombinase activities Alliance mouse Tcf21 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcf21 Mutation: 14 strains or lines available

References

• Original: J:334866 Peng YJ, et al., Sertoli cells are the source of stem cell factor for spermatogenesis. Development. 2023 Mar 15;150(6):dev200706
• All: 1 reference(s)