Del(Mup4-Mup21)1Fcw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(Mup4-Mup21)1Fcw
• Name: deletion, chr4, Fengchao Wang 1
• MGI ID: MGI:7462381
• Synonyms: Mup-knockout
• Gene: Del(Mup4-Mup21)1Fcw Location: unknown Genetic Position: Chr4, Syntenic

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Del(Mup4-Mup21)1Fcw involves 54 genes/genome features (Mup4, Mup6, Mup7 ...) View all
• Mutation details: CRIPSR/Cas9 genome editing technology was used to generate a 2.2 Mb deletion of the Mup gene cluster. The genomic region including chr4:59956711-62069136 (Grcmr39, reported in the publication as Grcm38 coordinates chr4:59956711-62150899) was deleted. (J:334686)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(Mup4-Mup21)1Fcw Mutation: 0 strains or lines available

References

• Original: J:334686 Yang H, et al., Mup-knockout mice generated through CRISPR/Cas9-mediated deletion for use in urinary protein analysis. Acta Biochim Biophys Sin (Shanghai). 2016 May;48(5):468-73
• All: 2 reference(s)