Psmb10^em1Jwk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Psmb10^em1Jwk
• Name: proteasome (prosome, macropain) subunit, beta type 10; endonuclease-mediated mutation 1, Jin Woo Kim
• MGI ID: MGI:7460353
• Synonyms: Psmb10^-, Psmb10em1Jwk
• Gene: Psmb10 Location: Chr8:106662360-106665024 bp, - strand Genetic Position: Chr8, 53.06 cM
• Alliance: Psmb10^em1Jwk page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Using the CRISPR/Cas9 system, 22 nucleotide (nt) deletions were made in the mouse Psmb10 gene. (J:314167)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Psmb10 Mutation: 16 strains or lines available

References

• Original: J:314167 Lim S, et al., mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Muller glia. Elife. 2021 Oct 22;10:e70079
• All: 1 reference(s)