Psmb8^em1Hwl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Psmb8^em1Hwl
• Name: proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7); endonuclease-mediated mutation 1, Han-Woong Lee
• MGI ID: MGI:7460351
• Synonyms: Psmb8^-, Psmb8em1hwl
• Gene: Psmb8 Location: Chr17:34417169-34420428 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: Psmb8^em1Hwl page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Using the CRISPR/Cas9 system, 25 nucleotide (nt) deletions were made in the mouse Psmb8 gene. (J:334523)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Psmb8 Mutation: 15 strains or lines available

References

• Original: J:334523 Hidema S, et al., Transgenic expression of Telomerase reverse transcriptase (Tert) improves cell proliferation of primary cells and enhances reprogramming efficiency into the induced pluripotent stem cell. Biosci Biotechnol Biochem. 2016 Oct;80(10):1925-33
• All: 1 reference(s)