Tg(MMTV-PRUNE1)1Nmrn
Transgene Detail

Summary

• Symbol: Tg(MMTV-PRUNE1)1Nmrn
• Name: transgene insertion 1, Natascia Marino
• MGI ID: MGI:7451259
• Synonyms: MMTV-Prune-1
• Transgene: Tg(MMTV-PRUNE1)1Nmrn Location: unknown Genetic Position: ChrUN, Syntenic
• Alliance: Tg(MMTV-PRUNE1)1Nmrn page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains the MMTV promoter driving mammary gland-specific expression of the human gene. Line 1 was used as the representative line. (J:306789)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:306789 Ferrucci V, et al., Prune-1 drives polarization of tumor-associated macrophages (TAMs) within the lung metastatic niche in triple-negative breast cancer. iScience. 2021 Jan 22;24(1):101938
• All: 1 reference(s)