Glul^em1Bzsh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Glul^em1Bzsh
• Name: glutamate-ammonia ligase; endonuclease-mediated mutation 1, Bin Zhou
• MGI ID: MGI:7451135
• Synonyms: GS-flagBFP
• Gene: Glul Location: Chr1:153775692-153785469 bp, + strand Genetic Position: Chr1, 65.43 cM, cytoband G2
• Alliance: Glul^em1Bzsh page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: Using CRISPR/Cas9 technology, a cDNA encoding flag-tagged BFP was inserted into the translational stop codon of the Glul gene, following endogenous Glul by the self-cleaving peptide 2A sequence. (J:303771)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Glul Mutation: 33 strains or lines available

References

• Original: J:303771 He L, et al., Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair. Science. 2021 Feb 26;371(6532)
• All: 1 reference(s)