Fzd2^em1Rstot
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fzd2^em1Rstot
• Name: frizzled class receptor 2; endonuclease-mediated mutation 1, Rolf Stottmann
• MGI ID: MGI:7450775
• Synonyms: Fzd2^D3, Fzd2^em1Rstot(D3)
• Gene: Fzd2 Location: Chr11:102495257-102498884 bp, + strand Genetic Position: Chr11, 66.45 cM
• Alliance: Fzd2^em1Rstot page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 3 bp encoding serine at position 552. (J:333565)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fzd2 Mutation: 32 strains or lines available

References

• Original: J:333565 Liegel RP, et al., Successful therapeutic intervention in new mouse models of frizzled 2-associated congenital malformations. Development. 2023 Feb 1;150(3):dev201038
• All: 1 reference(s)