Dlk1^em3(Sox4)Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dlk1^em3(Sox4)Gpt
• Name: delta like non-canonical Notch ligand 1; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
• MGI ID: MGI:7449110
• Synonyms: Pref1-Sox4
• Gene: Dlk1 Location: Chr12:109418749-109429262 bp, + strand Genetic Position: Chr12, 60.17 cM, cytoband E-F1
• Alliance: Dlk1^em3(Sox4)Gpt page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutation: Insertion
• Dlk1^em3(Sox4)Gpt expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Sox4 (MGI:98366)

• The full-length mouse Sox4 cDNA was inserted directly after 6 kb of the Dlk1 promoter. (J:334221)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dlk1 Mutation: 36 strains or lines available

References

• Original: J:334221 Shen H, et al., SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARgamma complex. Theranostics. 2022;12(18):7699-7716
• All: 1 reference(s)