S100a8^tm1.1Jshir
Targeted Allele Detail

Summary

• Symbol: S100a8^tm1.1Jshir
• Name: S100 calcium binding protein A8 (calgranulin A); targeted mutation 1.1, Jun Shirakawa
• MGI ID: MGI:7448954
• Synonyms: S100A8^floxed
• Gene: S100a8 Location: Chr3:90576378-90577341 bp, + strand Genetic Position: Chr3, 39.9 cM, cytoband F1-F2
• Alliance: S100a8^tm1.1Jshir page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:334321
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct flanked a 516 bp region containing exons 2 and 3. Recombination removed the selection cassette. (J:334321)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any S100a8 Mutation: 11 strains or lines available

References

• Original: J:334321 Miyashita D, et al., Protective effects of S100A8 on sepsis mortality: Links to sepsis risk in obesity and diabetes. iScience. 2022 Dec 22;25(12):105662
• All: 1 reference(s)