Tg(Rr61430-mCherry)LBmutKmor
Transgene Detail

Summary

• Symbol: Tg(Rr61430-mCherry)LBmutKmor
• Name: transgene insertion LBmut, Ken-ichirou Morohashi
• MGI ID: MGI:7448557
• Synonyms: mFLE-mCherry
• Transgene: Tg(Rr61430-mCherry)LBmutKmor Location: unknown
• Alliance: Tg(Rr61430-mCherry)LBmutKmor page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene insert contains the following elements: 1.8 kb sequence from ~3.5kb downstream of Nr5a1 containing a fetal Leydig cell-specific Nr5a1 enhancer, 5.8 kb sequence containing Nr5a1 promoter (modified) and gene sequence up to and including 5' UTR on exon 2, the mCherry reporter gene, and SV40 poly(A) signal sequences. The modification of the promoter entails two point mutations that abolish an LHX9-binding site. (J:334323)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:334323 Miyabayashi K, et al., Heterogeneity of ovarian theca and interstitial gland cells in mice. PLoS One. 2015;10(6):e0128352
• All: 1 reference(s)