Ncor2tm1.1Mafa
Targeted Allele Detail
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Symbol: |
Ncor2tm1.1Mafa |
Name: |
nuclear receptor co-repressor 2; targeted mutation 1.1, Michael A Farrar |
MGI ID: |
MGI:7444818 |
Synonyms: |
Ncor2FL |
Gene: |
Ncor2 Location: Chr5:125094217-125256283 bp, - strand Genetic Position: Chr5, 63.96 cM, cytoband F
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Alliance: |
Ncor2tm1.1Mafa page
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Germline Transmission: |
Earliest citation of germline transmission:
J:333184
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: The targeting construct inserted into intron 1 an FRT site, F3 site, loxP site, lox511, splice acceptor, beta-galactosidase gene, polyadenylation sequence, loxP site, lox511 site, FRT site, and F3 site. Flp-mediated recombination inverted the cassette allowing for normal gene splicing until crossed with a cre recombinase expressing gene.
(J:333184)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ncor2 Mutation: |
170 strains or lines available
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Original: |
J:333184 Lee RD, et al., Nuclear corepressors NCOR1/NCOR2 regulate B cell development, maintain genomic integrity and prevent transformation. Nat Immunol. 2022 Dec;23(12):1763-1776 |
All: |
2 reference(s) |
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