Slc4a4^tm2.1Ges
Targeted Allele Detail

Summary

• Symbol: Slc4a4^tm2.1Ges
• Name: solute carrier family 4 (anion exchanger), member 4; targeted mutation 2.1, Gary E Shull
• MGI ID: MGI:7444517
• Synonyms: Slc4a4^flx
• Gene: Slc4a4 Location: Chr5:89034345-89387512 bp, + strand Genetic Position: Chr5, 44.1 cM, cytoband E2
• Alliance: Slc4a4^tm2.1Ges page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333736
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exon 12. Flp-mediated recombination removed the selection cassette. (J:333736)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc4a4 Mutation: 81 strains or lines available

References

• Original: J:333736 Vairamani K, et al., NBCe1 Na(+)-HCO3(-) cotransporter ablation causes reduced apoptosis following cardiac ischemia-reperfusion injury in vivo. World J Cardiol. 2018 Sep 26;10(9):97-109
• All: 5 reference(s)