Nlgn2^tm1.1Kbd
Targeted Allele Detail

Summary

• Symbol: Nlgn2^tm1.1Kbd
• Name: neuroligin 2; targeted mutation 1.1, Dilja Krueger-Burg
• MGI ID: MGI:7442626
• Gene: Nlgn2 Location: Chr11:69713949-69728610 bp, - strand Genetic Position: Chr11, 42.89 cM
• Alliance: Nlgn2^tm1.1Kbd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314466
• Parent Cell Line: JM8A3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT-flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:314466)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlgn2 Mutation: 33 strains or lines available

References

• Original: J:314466 Cruces-Solis H, et al., Altered theta and beta oscillatory synchrony in a genetic mouse model of pathological anxiety. FASEB J. 2021 Jun;35(6):e21585
• All: 1 reference(s)