Tg(Rr387-lacZ)12Jejo
Transgene Detail

Summary

• Symbol: Tg(Rr387-lacZ)12Jejo
• Name: transgene insertion 12, Jane E Johnson
• MGI ID: MGI:7442605
• Transgene: Tg(Rr387-lacZ)12Jejo Location: unknown
• Alliance: Tg(Rr387-lacZ)12Jejo page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene insertion contains the following elements: a SacII-SmaI restriction fragment containing sequence downstream of Atoh1 (which includes enhancer Rr387 or E0) where the last 144 bp were deleted and the E-box at he 3' end was mutated from CAGctg to ATTctg, Hbb basal promoter, the beta-galactosidase reporter gene, and SV40 ploy(A) signal sequences. Reporter gene embryonic expression is abolished in the dorsal neural tube but still present, weakly, in hindbrain. (J:60854)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:60854 Helms AW, et al., Autoregulation and multiple enhancers control Math1 expression in the developing nervous system. Development. 2000 Mar;127(6):1185-96
• All: 1 reference(s)