Tg(Atoh1-lacZ)4Jejo
Transgene Detail

Summary

• Symbol: Tg(Atoh1-lacZ)4Jejo
• Name: transgene insertion 4, Jane E Johnson
• MGI ID: MGI:7442594
• Transgene: Tg(Atoh1-lacZ)4Jejo Location: unknown
• Alliance: Tg(Atoh1-lacZ)4Jejo page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: This transgene was created by coinjection of two overlapping genomic fragments: an NcoI-NcoI restriction fragment containing sequence 5' to and 3' from the Atoh1 coding sequence and a BglII-BglII fragment containing the last ~400 bp of coding sequence and 6 kb 3' of the coding region. The coding sequence between the first ~2.5 kb and the last ~1.5 kb was replaced in-frame with the beta-galactosidase reporter gene (without NLS sequence). (J:60854)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:60854 Helms AW, et al., Autoregulation and multiple enhancers control Math1 expression in the developing nervous system. Development. 2000 Mar;127(6):1185-96
• All: 1 reference(s)