Mir191^tm1.1Qjl
Targeted Allele Detail

Summary

• Symbol: Mir191^tm1.1Qjl
• Name: microRNA 191; targeted mutation 1.1, Qi-Jing Li
• MGI ID: MGI:7442500
• Gene: Mir191 Location: Chr9:108445518-108445591 bp, + strand Genetic Position: Chr9, 59.5 cM
• Alliance: Mir191^tm1.1Qjl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314799
• Parent Cell Line: PRX-B6N (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the sequence and an FRT flanked pgk-neo cassette and loxP site were inserted downstream of the sequence via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:314799)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir191 Mutation: 2 strains or lines available

References

• Original: J:314799 Lykken EA, et al., The MicroRNA miR-191 Supports T Cell Survival Following Common gamma Chain Signaling. J Biol Chem. 2016 Nov 4;291(45):23532-23544
• All: 1 reference(s)