Gcg^{tm1(cre/ERT2)Cshi}
Targeted Allele Detail

Summary

• Symbol: Gcg^{tm1(cre/ERT2)Cshi}
• Name: glucagon; targeted mutation 1, Chiyo Shiota
• MGI ID: MGI:7439833
• Synonyms: Gcg-RSR-CreERT2, Gcg^{tm1(RSR/cre/ERT2)Cshi}
• Gene: Gcg Location: Chr2:62304874-62313994 bp, - strand Genetic Position: Chr2, 35.85 cM
• Alliance: Gcg^{tm1(cre/ERT2)Cshi} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting construct is designed to insert a rox-flanked STOP cassette (RSR) followed by a creERT2 and an FRT-flanked neomycin resistance (neo) cassette into exon 2 of the gene. Expression of CreERT2 driven by the endogenous Gcg gene promoter occurs only after the removal of RSR by Dre recombinase. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gcg Mutation: 34 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)