Tg(A94G6*)#Rub
Transgene Detail

Summary

• Symbol: Tg(A94G6*)#Rub
• Name: transgene insertion, Edward M Rubin
• MGI ID: MGI:7439485
• Synonyms: CNS-1^del
• Transgene: Tg(A94G6*)#Rub Location: unknown
• Alliance: Tg(A94G6*)#Rub page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The insertion comprises human YAC A94G6, modified to flank the CNS-1 (conserved non-coding sequence 1) sequence, between IL4 and IL13, with loxP sites. The CNS-1 sequence was deleted through subsequent cre-mediated recombination. The YAC contains the 3' end of KIF3A, the IL4, IL13, RAD50, IL5, IRF1, IRF1-AS1 and SLC22A5 genes, and the 3' end of SLC22A4. (J:61463)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:61463 Loots GG, et al., Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons [see comments]. Science. 2000 Apr 7;288(5463):136-40
• All: 1 reference(s)