Gt(ROSA)26Sor^{tm1.1(CAG-Tfap2e)Forni}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.1(CAG-Tfap2e)Forni}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Paolo E Forni
• MGI ID: MGI:7439399
• Synonyms: Gt(ROSA)26Sor^{tm(CAG-mTfap2e)For}, R26AP-2epsilon
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.1(CAG-Tfap2e)Forni} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333538
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1.1(CAG-Tfap2e)Forni} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tfap2e (MGI:2679630)

• Mutation details: A CAG promotor-loxP-stop-loxP mouse Tfap2e coding sequence-polyA cassette was inserted into intron 1. A neomycin selection maker flanked by self-deletion anchor (SDA) sites that was inserted was self-deleted. (J:333538)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 944 strains or lines available

References

• Original: J:333538 Lin JM, et al., Sociosexual behavior requires both activating and repressive roles of Tfap2e/AP-2epsilon in vomeronasal sensory neurons. Elife. 2022 Sep 16;11:e77259
• All: 1 reference(s)