Nppa^{tm1.1(Hbegf/EGFP)Bzsh}
Targeted Allele Detail

Summary

• Symbol: Nppa^{tm1.1(Hbegf/EGFP)Bzsh}
• Name: natriuretic peptide type A; targeted mutation 1.1, Bin Zhou
• MGI ID: MGI:7439140
• Synonyms: Nppa-GFP, Nppa^{tm1.1(DTR/EGFP)Bzsh}
• Gene: Nppa Location: Chr4:148085179-148086531 bp, + strand Genetic Position: Chr4, 78.66 cM
• Alliance: Nppa^{tm1.1(Hbegf/EGFP)Bzsh} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263128
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Nppa^{tm1.1(Hbegf/EGFP)Bzsh} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Hbegf

• Mutation details: A cDNAs-encoding DTR/GFP fusion protein was inserted in frame with the translational start codon of the Nppa gene. (J:263128)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nppa Mutation: 12 strains or lines available

References

• Original: J:263128 Tian X, et al., Identification of a hybrid myocardial zone in the mammalian heart after birth. Nat Commun. 2017 Jul 20;8(1):87
• All: 1 reference(s)