Tg(Tph1-EGFP/cre/ERT2)#Jmer
Transgene Detail

Summary

• Symbol: Tg(Tph1-EGFP/cre/ERT2)#Jmer
• Name: transgene insertion, Juanita L Merchant
• MGI ID: MGI:7439062
• Synonyms: Tph1-CreERT2
• Transgene: Tg(Tph1-EGFP/cre/ERT2)#Jmer Location: unknown
• Alliance: Tg(Tph1-EGFP/cre/ERT2)#Jmer page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Tph1-EGFP/cre/ERT2)#Jmer expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tph1 (MGI:98796)

• Mutation details: A 3,718-bp cassette containing the fusion of sequence-encoding enhanced green fluorescent protein (eGFP), Cre recombinase, and the mutant estrogen ligand-binding domain (ERT2) was inserted into a BAC clone (RP23-29A7) containing the full-length gene encoding Tph1 at the ATG start codon. The eGFP protein fluorescence expression is not detectable. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:333475)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tph1 (mouse) Summary of all recombinase alleles driven by Tph1. Comparative matrix view of recombinase activities Alliance mouse Tph1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:333475 Sei Y, et al., Mature enteroendocrine cells contribute to basal and pathological stem cell dynamics in the small intestine. Am J Physiol Gastrointest Liver Physiol. 2018 Oct 1;315(4):G495-G510
• All: 3 reference(s)