Iigp1c^em2Btlr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Iigp1c^em2Btlr
• Name: interferon inducible GTPase 1C; endonuclease-mediated mutation 2, Bruce Beutler
• MGI ID: MGI:7439060
• Synonyms: 3xFlag-Gm4951, Gm4951^em2Btlr
• Gene: Iigp1c Location: Chr18:60345152-60380892 bp, + strand Genetic Position: Chr18, 34.36 cM
• Alliance: Iigp1c^em2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• CRISPR-targeting inserted a triple FLAG-tag at the translation initiation site in exon 3. (J:333470)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Iigp1c Mutation: 16 strains or lines available

References

• Original: J:333470 Zhang Z, et al., Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity. Nat Commun. 2022 Jul 16;13(1):4136
• All: 1 reference(s)