Krt15^em1Yyang
Endonuclease-mediated Allele Detail

Summary

• Symbol: Krt15^em1Yyang
• Name: keratin 15; endonuclease-mediated mutation 1, Yong Yang
• MGI ID: MGI:7439047
• Synonyms: K15-knockout
• Gene: Krt15 Location: Chr11:100022584-100026754 bp, - strand Genetic Position: Chr11, 63.41 cM
• Alliance: Krt15^em1Yyang page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Using CRISPR-Cas9 gene-editing system, deletion was made within the Krt15 gene. (J:333463)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Krt15 Mutation: 27 strains or lines available

References

• Original: J:333463 Cui J, et al., KLHL24-Mediated Hair Follicle Stem Cells Structural Disruption Causes Alopecia. J Invest Dermatol. 2022 Aug;142(8):2079-2087.e8
• All: 1 reference(s)