Ikzf2^tm1Tnom
Targeted Allele Detail

Summary

• Symbol: Ikzf2^tm1Tnom
• Name: IKAROS family zinc finger 2; targeted mutation 1, Takashi Nomura
• MGI ID: MGI:7437740
• Synonyms: Helios^Venus
• Gene: Ikzf2 Location: Chr1:69570373-69726404 bp, - strand Genetic Position: Chr1, 34.9 cM
• Alliance: Ikzf2^tm1Tnom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:325570
• Parent Cell Line: KY1.1 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Venus cDNA, encoding a variant of green fluorescent protein (GFP), was inserted downstream of the first ATG of Helios through homologous recombination. (J:325570)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ikzf2 Mutation: 38 strains or lines available

References

• Original: J:325570 Sugita K, et al., Generation of Helios reporter mice and an evaluation of the suppressive capacity of Helios(+) regulatory T cells in vitro. Exp Dermatol. 2015 Jul;24(7):554-6
• All: 2 reference(s)