Kif2a^tm1.1Fati
Targeted Allele Detail

Summary

• Symbol: Kif2a^tm1.1Fati
• Name: kinesin family member 2A; targeted mutation 1.1, Fadel Tissir
• MGI ID: MGI:7435697
• Synonyms: Kif2a^f
• Gene: Kif2a Location: Chr13:107095504-107158634 bp, - strand Genetic Position: Chr13, 58.06 cM, cytoband F
• Alliance: Kif2a^tm1.1Fati page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333076
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The L1L2_Bact_P cassette R3R4_pBR_DTA+_Bsd_amp backbone from IKMC project 77718 was used to generate this allele. A cassette containing FRTEngrailed2 exon IRESLacZloxPneoFRTloxP was inserted in intron 7, and a loxP was inserted in intron 10. The lacZ and neo were removed via flp-mediated recombination leaving exons 8-10 floxed. (J:333076)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif2a Mutation: 27 strains or lines available

References

• Original: J:333076 Hakanen J, et al., The Celsr3-Kif2a axis directs neuronal migration in the postnatal brain. Prog Neurobiol. 2022 Jan;208:102177
• All: 2 reference(s)