Rr360^tm1Bcgen
Targeted Allele Detail

Summary

• Symbol: Rr360^tm1Bcgen
• Name: regulatory region 360; targeted mutation 1, Biocytogen LLC
• MGI ID: MGI:7435007
• Synonyms: Nampt^NRE-fl
• Gene: Rr360 Location: Chr12:32871048-32877795 bp Genetic Position: Chr12, Syntenic
• Alliance: Rr360^tm1Bcgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333205
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, Modified regulatory region)
• Mutation: Insertion
• The Nampt enhancer in intron 1, containing Stat1-binding sites, was flanked by loxP sites. (J:333205)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr360 Mutation: 0 strains or lines available

References

• Original: J:333205 Huffaker TB, et al., A Stat1 bound enhancer promotes Nampt expression and function within tumor associated macrophages. Nat Commun. 2021 May 11;12(1):2620
• All: 1 reference(s)