Gpr89em1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Gpr89em1(IMPC)J |
Name: |
G protein-coupled receptor 89; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:7434700 |
Gene: |
Gpr89 Location: Chr3:96775630-96812662 bp, - strand Genetic Position: Chr3, 42.01 cM, cytoband F2
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Alliance: |
Gpr89em1(IMPC)J page
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IMPC: |
Gpr89 gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTAGTCACATAAGATTTACA and CCATGGGTCGTATTCAGCAT, which resulted in a 1011 bp deletion beginning at Chromosome 3 position 96,892,679 bp and ending after 96,893,689 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001216982 and ENSMUSE00001294364 (exons 4 and 5) and 802 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 68 and early truncation 44 amino acids later.
(J:188991)
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Inheritance: |
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Not Specified |
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
1 reference(s) |
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